Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis, 3rd Edition, 生体組織光学、光散乱法や医療診断のための機器, 第3版, 9781628415162, 978-1-62841-516-2

書名

Tissue Optics: Light Scattering Methods and Instruments for Medical Diagnosis, 3rd Edition
生体組織光学、光散乱法や医療診断のための機器, 第3版
著者・編者 Tuchin, V.V.
発行元 SPIE
発行年/月 2015年2月   
装丁 Hardcover
ページ数 988 ページ
ISBN 978-1-62841-516-2
発送予定 海外倉庫よりお取り寄せ 3-5週間以内に発送します
 

Description

This third edition of the biomedical optics classic Tissue Optics covers the continued intensive growth in tissue optics-in particular, the field of tissue diagnostics and imaging-that has occurred since 2007. As in the first two editions, Part I describes fundamentals and basic research, and Part II presents instrumentation and medical applications. However, for the reader’s convenience, this third edition has been reorganized into 14 chapters instead of 9. The chapters covering optical coherence tomography, digital holography and interferometry, controlling optical properties of tissues, nonlinear spectroscopy, and imaging have all been substantially updated.

The book is intended for researchers, teachers, and graduate and undergraduate students specializing in the physics of living systems, biomedical optics and biophotonics, laser biophysics, and applications of lasers in biomedicine. It can also be used as a textbook for courses in medical physics, medical engineering, and medical biology.

 

Contents:

PART I INTRODUCTION TO TISSUE OPTICS
1 Optical Properties of Tissues with Strong (Multiple) Scattering
1.1 Propagation of Continuous Wave Light in Tissues
1.1.1 Basic principles and major scatterers and absorbers
1.1.2 Theoretical description
1.1.3 Monte Carlo simulation techniques
1.2 Short Pulse Propagation in Tissues
1.2.1 Basic principles and theoretical background
1.2.2 Techniques for time-resolved spectroscopy and imaging
1.2.3 Coherent backscattering
1.3 Diffuse Photon-Density Waves
1.3.1 Basic principles and theoretical background
1.3.2 Principles of FD spectroscopy and imaging of tissues
1.4 Spatially Modulated Light Propagation in Tissues
1.4.1 Introduction
1.4.2 Theory and measurement of diffuse light spatial frequency spectrum
1.4.3 Spatially modulated spectroscopy and imaging of tissues
1.5 Conclusion

2 Electrical, Optical, and Structural Studies of InAs/InGaSb VLWIR Superlattices
2.1 Introduction
2.2 Tissue Structure and Anisotropy
2.3 Light Scattering by a Particle
2.4 Description and Detection of Polarized Light
2.5 Light Interaction with a Random Single-Scattering Media
2.6 Vector Radiative Transfer Equation
2.7 Monte Carlo Simulation
2.8 Strongly Scattering Tissues and Phantoms

3 Discrete Particle Models of Tissue
3.1 Introduction
3.2 Refractive-Index Variations of Tissue
3.3 Particle Size Distributions
3.4 Spatial Ordering of Particles
3.5 Scattering by Densely Packed Particle Systems
3.6 Optical Properties of Eye Tissues
3.6.1 Optical models
3.6.1 Spectral characteristics
3.6.3 Polarization properties

4 Optothermal, Optoacoustic, and Acousto-Optic Interactions of Light with Tissues
4.1 Basic Principles and Classification
4.2 OA/PA Gas Cell Technique
4.3 Modulated (Phase) OA/PA Technique
4.4 Pulsed OA/PA
4.5 Grounds of OA/PA Tomography and Microscopy
4.6 Optothermal Radiometry
4.7 Optothermal Spectroscopy and Imaging
4.8 Acousto-Optical Interactions
4.9 Thermal Effects
4.10 Sonoluminescence
4.11 Prospective Applications and Measuring Techniques
4.11.1 Vascular imaging
4.11.2 Glucose monitoring
4.11.3 Quantification of total hemoglobin and blood oxygenation
4.11.4 Temperature measurement and monitoring temperature effects
4.11.5 In vivo cytometry and imaging of sentinel lymph nodes
4.11.6 OA/PA aensors and systems
4.12 Conclusion

5 Fluorescence and Inelastic Light Scattering
5.1 Fluorescence
5.2 Multiphoton Fluorescence
5.3 Vibrational and Raman Spectroscopies

6 Tissue Phantoms
6.1 Introduction
6.2 Concepts of Phantom Construction
6.3 Examples of Designed Tissue Phantoms
6.4 Examples of Whole Organ Models
6.5 Summary

7 Methods and Algorithms for Measurement of the Optical Parameters of Tissues
7.1 Basic Principles
7.2 Integrating Sphere Technique
7.3 Multiflux Models
7.4 Inverse Adding-Doubling Method
7.5 Inverse Monte Carlo Method
7.6 Spatially Resolved Techniques
7.7 Optical Coherence Tomography
7.8 Direct Measurement of the Scattering Phase Function
7.9 Estimates of the Optical Properties of Tissues
7.10 Determination of Optical Properties of Blood
7.11 Measurements of Tissue Penetration Depth and Light Dosimetry
7.12 Refractive Index Measurements

8. Coherent Effects at the Interaction of Laser Radiation with Tissues and Cell Flows
8.1 Formation of Speckle Structures
8.2 Interference of Speckle Fields
8.3 Propagation of Spatially Modulated Laser Beams in a Scattering Medium
8.4 Dynamic Light Scattering
8.4.1 Quasi-elastic light scattering
8.4.2 Dynamic speckles
8.4.3 Full-field speckle technique: LASCA
8.4.4 Diffusion wave spectroscopy
8.5 Confocal Microscopy
8.6 Optical Coherence Tomography
8.7 Digital Holographic and Interferential Microscopy
8.8 Second Harmonic Generation and Nonlinear Raman Scattering
8.9 Terahertz Spectroscopy and Imaging

9. Controlling Optical Properties of Tissues
9.1 Fundamentals of Controlling Optical Properties of Tissue and Brief Review
9.2 Tissue Optical Immersion by Exogenous Chemical Agents
9.2.1 Principles of optical immersion technique
9.2.2 Water transport
9.2.3 Tissue swelling and hydration
9.3 Optical Clearing of Fibrous Tissues
9.3.1 Spectral properties of immersed sclera
9.3.2 Scleral in vitro frequency-domain measurements
9.3.3 Scleral in vivo measurements
9.3.4 OCT monitoring of OCA and drug delivery in eye sclera and cornea
9.3.5 Dura mater immersion and agent diffusion rate
9.4 Skin
9.4.1 Introduction
9.4.2 In vitro spectral measurements
9.4.3 In vivo spectral reflectance measurements
9.4.4 In vivo frequency-domain measurements
9.4.5 OCT imaging
9.4.6 OCA delivery, skin permeation, and reservoir function
9.5 Optical Clearing of Digestive Tract Tissue
9.5.1 Spectral measurements
9.5.2 OCT imaging
9.6 Optical Clearing of Other Tissues
9.6.1 Muscle
9.6.2 Breast and lung
9.6.3 Cranial bone
9.6.4 Tooth dentin
9.7 Other Prospective Optical Techniques
9.7.1 Polarization measurements
9.7.2 Confocal microscopy
9.7.3 Fluorescence detection
9.7.4 Two-photon scanning fluorescence microscopy
9.7.5 Second harmonic generation
9.7.6 Vibrational, Raman, and CARS spectroscopy
9.7.7 Tissue clearing in the terahertz range
9.8 Imaging of Cells and Cell Flows
9.8.1 Blood flow imaging
9.8.2 Optical clearing of blood
9.8.3 Cell studies
9.8.4 "Self-clearing" or metabolic clearing effects
9.9 Applications of the Tissue Immersion Technique
9.9.1 Glucose sensing
9.9.2 Characterization of atherosclerotic vascular tissues
9.9.3 Optical imaging of lymph nodes
9.9.4 Precision femtosecond laser surgery
9.9.5 Skin tattoo imaging and laser removal
9.10 Other Techniques for Controlling Tissue Optical Properties
9.10.1 Tissue compression and stretching
9.10.2 Temperature effects and tissue coagulation
9.10.3 Tissue whitening
9.11 Conclusion

PART II LIGHT-SCATTERING METHODS AND INSTRUMENTS FOR MEDICAL DIAGNOSIS
10 Continuous Wave Spectrophotometry and Imaging
10.1 Techniques and Instruments for in vivo Spectroscopy and Imaging of Tissues
10.2 Example of the Spectroscopic System
10.3 Example of the Imaging System
10.4 Light Scattering Spectroscopy
COLOR PLATE SECTION

11 Time-Resolved and Spatially Modulated Spectroscopy and Tomography of Tissues
11.1 Time-Domain Techniques and Instruments
11.2 Frequency-Domain Techniques and Instruments
11.3 Phased-Array Technique
11.4 In vivo Measurements, Detection Limits, and Examples of Clinical Study
11.5 Spatially Modulated Method

12 Polarization-Sensitive Techniques
12.1 Polarization Imaging
12.1.1 Transillumination polarization technique
12.1.2 Backscattering polarization imaging
12.2 Polarized Reflectance Spectroscopy of Tissues
12.2.1 In-depth polarization spectroscopy
12.2.2 Superficial epithelial layer polarization spectroscopy
12.3 Polarization Microscopy
12.4 Digital Photoelasticity Measurements
12.5 Fluorescence Polarization Measurements
12.6 Conclusion

13 Coherence-Domain Methods and Instruments for Biomedical Diagnostics and Imaging
13.1 Photon-Correlation Spectroscopy of Transparent Tissues and Cell Flows
13.1.1 Introduction
13.1.2 Cataract diagnostics
13.1.3 Blood and lymph flow monitoring in microvessels
13.2 Diffusion-Wave Spectroscopy and Interferometry: Measurement of Blood Microcirculation
13.3 Blood Flow Imaging
13.4 Interferometric and Speckle-Interferometric Methods for the Measurement of Biovibrations
13.5 Optical Speckle Topography and Tomography of Tissues
13.6 Methods of Coherent Microscopy
13.7 Interferential Retinometry and Blood Sedimentation Study

14 Optical Coherence Tomography and Heterodye Imaging
14.1 Optical Coherence Tomography
14.1.1 Introduction
14.1.2 Time-domain OCT
14.1.3 Two-wavelength fiber OCT
14.1.4 Ultrahigh-resolution fiber OCT
14.1.5 Frequency-domain OCT
14.1.6 Doppler OCT and blood flow measurements
14.1.7 Polarization sensitive OCT
14.1.8 Phase-sensitive OCT
14.1.9 Optical coherence elastography
14.1.10 Full-field OCT
14.1.11 Optical coherence microscopy
14.1.12 Endoscopic OCT
14.1.13 Speckle OCT
14.1.14 OCT quantitative parametric imaging of attenuation
14.1.15 Combined OCT systems
14.2 Optical Heterodyne Imaging
14.3 Summary